To the Editor: Dandy-Walker variant, characterized by cerebellar hypoplasia without marked expansion of the posterior fossa, has been classified as a continuum of Dandy-Walker malformation. We report a case of a Dandy-Walker variant in association with schizophrenia, in which there was worsening of tardive dyskinesia with low doses of atypical antipsychotics. The Dandy-Walker malformation is a congenital brain malformation characterized by cystic dilatation of the fourth ventricle, dysgenesis of the cerebellar vermis, and higher position of tentorium.

Background: Clozapine induced granulocytopenia has gained wide attention and effective monitoring has been able to prevent a number of untoward deaths. However, other myelodysplasias induced by Clozapine are still unrecognized and unreported. Another clinical complication of Clozapine is eosinophilia. However, this entity is unrecognized as the focus is mostly on granulocytopenia and neutropenia. Objective: To describe a case of Clozapine induced eosinophilia without any other clinical or biochemical abnormalities induced by Clozapine.